Pro+ Bio Resurfacing Retinol RX

$88.00 Sale Save
Size: 50mL

This gentle leave on granactive retinoid serum contains AZA, niacinamide, liquorice root extract and zinc & copper gluconates to help calm redness and improve the skin’s appearance.

Our Pro+ Bio Resurfacing Retinol RX serum is the first probiotic retinol to market that has been specially formulated for use for even the most sensitive skins. This granactive retinoid serum includes ingredients to help negate any irritation you would normally get with other retinols. If you are wanting to work up to this please start with our Pro+ Bio Resurfacing Retinol ALT which is a plant based retinol alternative that contains Bakuchiol.

This product is not pregnancy or breastfeeding safe.

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AMPERNA® Pro+ Bio Resurfacing Retinol RX [SUPERFOLIATE] serum contains azelaic acid salt, niacinamide, liquorice root extract and zinc & copper gluconates to help calm redness and improve the skin’s texture. Hero ingredient granactive retinoid helps renew skin plumpness, elasticity and hydration. AMPERNA®’s unique probiotic complex delivers good bacteria to your skin gently and effectively. The AMPERNA® range is suitable for all skin types and has been tested on eczema, dermatitis, perioral dermatitis, rosacea and acne prone skin.

Non-comedogenic. No nasties, tested on real people, Australian made and owned.

Need more help using AMPERNA® products? Visit our detailed regime page to download instructions for your bathroom.

Take 1-2 pumps of this serum and gently pat onto clean skin. Apply in the evening. Limit initial use, gradually increasing when tolerated.

Retinols can increase skin’s sensitivity to the sun. Always wear sunscreen and appropriate sun protection while using this product.

Not pregnancy or breastfeeding safe.

Caution - For topical external use only. Avoid direct contact with eyes and broken skin. Everyone's skin is different so we recommend you undertake a spot test in a small, discreet area to test for adverse reactions. In the rare event of an adverse reaction discontinue use.

Store below 30ºC out of direct sunlight.

Need more help using AMPERNA® products? Visit our detailed regime page.

Aqua, Potassium Azeloyl Diglycinate (Azelaic Acid Salt), Niacinamide (Vitamin B3), Lactococcus Ferment Lysate, Polyacrylate Crosspolymer-6, Glyceryl Stearate, PEG-100 Stearate, Yeast Ferment Extract (Bioferment Oligopeptide), Soy Amino Acid, Dimethyl Isosorbide, Hydroxypinacolone Retinoate (HPR - Retinoic Acid Ester), Sodium-L-Lactate, Magnesium Aspartate, Zinc Gluconate, Copper Gluconate, Calcium Gluconate, Bisabolol, Dipotassium Glycyrithizate, Avena Sativa (Oat) Extract, Glycyrrhiza Glabra (Liquorice) Root Extract, Isostearyl Alcohol, Boswellia Serrata Gum, Panthenol (Vitamin B5), Saccharide Isomerate, Allantoin, Hyaluronic Acid (HMW), Zinc Oxide, DMDM Hydantoin, Iodopropynyl Butylcarbamate.

Does not contain any live cultures.

Rest assured, AMPERNA® products include high percentages of actives so you can feel confident you are doing the best for your skin.

Does not Include Sulfates, Parabens, Petrochemicals and Mineral Oils, Vinyls, Phthalates, Phenoxyethanol, Synthetic Fragrance, Synthetic Colours or Bleaches, PPG, DEAS, TEA, Aluminium or Alumina.

Ingredients Explained

Hydroxypinacolone Retinoate (HPR – Retinoic Acid Ester)

which you might be familiar with as "granactive retinoid" helps diminish signs of ageing whilst being more gentle on skin that other forms of retinol. Granactive retinoids help skin turn over whilst helping to slow down the degeneration of collagen

AMPERNA Back of woman

Ingredients Explained

Lactococcus Ferment Lysate

is a non-living probiotic that helps stimulate the skin's renewal processes.

AMPERNA Heart on arm

Ingredients Explained

Yeast Ferment Extract (Bioferment Oligopeptide), Soy Amino Acid

help to stimulate skin renewal, they actively help refine & restore skin texture and radiance safely.

AMPERNA Woman posing with hands

Customer Reviews

Based on 14 reviews
Peter Harache
Skin enhancing

I have sensitive, dry skin so was a little anxious to try a retinol product but I’m so pleased I did. It’s been 2 months since I started using Superfoliate and I introduced it very slowly, starting with twice a week but now tolerating every 2nd night. This product has addresses both dryness and oiliness and my skin feels so comfortable and soft. It is also clearer and I don’t get many breakouts these days. I did have to push through some days of skin pinkness and dry patches but the result was worth it! Would highly recommend!


My derm prescribed me with retinol for continuous use, but it was too harsh for my skin. Decided to try this, and I'm so glad I did! I haven't had any irritation, and my skin looks great

J. O.
Gentle Retinol

Once the soothing duo got my PD flare up under control, I wanted to do something about my skin's hyperpigmentation and texture. I was apprehensive but this has been the gentlest yet effective retinol I have used. It has become a regular part of my routine.

Helen Liu
Glowing skin

I’ve been using the soothing serum for about a year (can’t go without it now!) and slowly started introducing this retinol in my skincare. This literally makes your skin glow the next day - even more than la mer! If you have sensitive skin, I find you do have to start gentle with this (once every 2-3 nights) before building up the frequency. Can’t wait to see the long term change this will have on my skin.

Loving this retinol

Other retinols have really bothered my skin- this one is wonderfully gentle but still really effective. Its another Amperna win for me!