Postbiotics Explained and Why Your Skin Needs Them

Postbiotics Explained and Why Your Skin Needs Them

The science behind our hero ingredient: Lactococcus Ferment Lysate

At AMPERNA® we focus on proven, science-backed ingredients that support your skin microbiome and soothe and promote calmer skin. Our hero ingredient doing just that is a powerful postbiotic called Lactococcus Ferment Lysate.

What Are Postbiotics

Postbiotics are the beneficial by-products created during the fermentation of probiotics (live beneficial bacteria). Unlike probiotics, postbiotics are non-living meaning they are more stable, safer for all skin types, and still deliver skin-supporting benefits.

At the heart of AMPERNA®’s active range is Lactococcus Ferment Lysate, a biotech-developed postbiotic derived from the Lactococcus lactis species. It is gently fermented to produce lysates (beneficial cell fragments packed with peptides, enzymes, and metabolites.)

We include this powerhouse ingredient in our formulations to support the skin’s natural renewal process, maintain the appearance of a healthy skin barrier, and improve the look of skin comfort.

5 Powerful Benefits of Postbiotics for Your Skin

1. Helps Maintain the Appearance of the Skin Barrier

Your skin barrier is your body’s first line of defence. When compromised, it can lead to redness, dryness, stinging and sensitivity. Postbiotics like Lactococcus Ferment Lysate help reinforce your skin’s natural structure by helping boost cell cohesion, encouraging faster skin renewal, and enhancing hydration retention.

Why it matters: A stronger skin barrier means reduced trans-epidermal water loss and more resilient skin overall.

2. Helps Soothe and Calm Red-Looking Skin

Postbiotics have been shown to help support the skin’s natural defences and promote a balanced-looking complexion. Lactococcus Ferment Lysate can help:

  • Soothe the appearance of red-looking skin.
  • Contributes to the look of a more balanced complexion.
  • Reduce the look of visible irritation and discomfort.

Perfect for: This gentle yet effective ingredient works with your skin making it ideal for those prone to sensitive skin.

3. Helps Boost Skin Renewal

Lactococcus Ferment Lysate is known to help support the skin’s natural renewal processes by encouraging optimal skin function. By promoting a balanced environment on the skin’s surface, this ingredient may assist in maintaining a smoother, healthier-looking complexion over time. Its gentle action makes it suitable for all skin types, including sensitive looking skin.

Use it when: You are experiencing barrier disruption from over-exfoliation, harsh actives, or environmental stress.

4. Helps Support a Healthy Skin Environment

Maintaining a healthy skin environment is essential for keeping skin looking calm, and resilient. When the skin barrier and microbiome are supported, the skin is better equipped to retain moisture and protect against external stressors. This leads to skin that looks more even, balanced, and healthy over time.

Suitable for: Skin prone to sensitivity, it helps support skin to feel calm, balanced, and comfortable.

5. Helps Skin Hydration

Postbiotics support the production of natural moisturising factors helping skin retain moisture and feel more comfortable. Lactococcus Ferment Lysate also supports skin to feel hydrated, soft, and comfortable.

Helpful for: All skin types, especially those living in dry climates, or people with dry-looking skin.

How Our Formulas Support the Power of Postbiotics

Each AMPERNA® formula is designed to work with your skin not against it. The carefully selected ingredients in each product help support and enhance the benefits of our postbiotic hero ingredient, Lactococcus Ferment Lysate, with a focus on synergy, skin health, and formulation integrity.

  • Gentle Formulations Help Preserve Skin Barrier Function:
    AMPERNA® uses calming, non-stripping ingredients that work in harmony with Lactococcus Ferment Lysate to avoid disrupting the skin barrier and allowing the postbiotic to support the skin’s natural renewal and resilience more effectively.
  • Hydrating Actives Enhance Postbiotic Function:
    Ingredients like hyaluronic acid and emollients help maintain skin hydration. A well-hydrated skin barrier allows postbiotics to perform optimally, supporting skin balance and comfort.
  • p.H-Balanced Formulas Respect the Skins Microbiome:
    AMPERNA® products are formulated to be pH-appropriate and free from known irritants, helping to create an ideal environment for Lactococcus Ferment Lysate to support a healthy-looking skin microbiome.
  • Antioxidant Support Skin Defences:
    AMPERNA®'s Pro+ Vitamin C Hyaluronic Serum provides antioxidant support, which helps reduce the visible effects of daily environmental stress. This complements Lactococcus Ferment Lysate’s role in supporting calm, resilient skin.
  • No Harsh Actives That Could Counteract Postbiotic Benefits:
    AMPERNA® avoids harsh exfoliants or high-dose actives that can overwhelm sensitive skin. This allows postbiotics to do their job effectively, helping to reduce the appearance of irritation and support a more balanced-looking complexion.

AMPERNA® Postbiotic Overview

By helping promote microbiome balance, reinforcing the skin’s natural defences, support the conditions that help maintain your skins natural p.H and boosting hydration, postbiotics can assist in keeping the skin looking calm, balanced, and resilient. Suitable for all skin types, including sensitive-prone skin, these gentle yet active formulations are designed to work with your skin to support its natural function and appearance.


References & additional reading:
Oral and Topical Probiotics and Postbiotics in Skincare and Dermatological Therapy: A Concise Review - PMC

*AMPERNA® products are cosmetic only and not intended to treat, cure or prevent any disease or skin condition. Always consult a healthcare professional for medical advice.